Research Article
Oxidative Stress Profile of Mothers and Their Offspring after Maternal Consumption of High-Fat Diet in Rodents: A Systematic Review and Meta-Analysis
Table 1
Maternal oxidative stress repercussions.
| References | Animal | Kcal of fat/main fat source | Maternal HFD consumption (days) | | Outcomes of dams | Sample evaluated | MDA | ROS | SOD | CAT | GPX | Scavenging capacity of reactive oxygen species |
| Lin et al., [25]a | Rats (Sprague–Dawley) | 40%/lard | 19 | ↑ | NM | NM | NM | NM | ↓ | Blood | Lin et al., [25]b | Rats (Sprague–Dawley) | 40%/lard | 19 | ↑ | NM | NM | NM | NM | ↓ | Placenta | Gonçalves et al., [44]a | Rats Wistar | 71%/lard | 42 | ↔ | NM | ↔ | ↔ | NM | NM | Liver | Gonçalves et al., [44]b | Rats Wistar | 71%/lard | 42 | ↔ | NM | NM | NM | NM | NM | Blood | Kim et al., [14]a | Mice (C57BL/6) | 45%/lard | 63 | ↑ | NM | NM | NM | NM | NM | Blood | Kim et al., [14]b | Mice (C57BL/6) | 45%/lard | 63 | ↑ | NM | NM | NM | NM | NM | Liver | Harphoush et al., [47]a | Mice (C57BL/6) | | 113 | ↑ | NM | ↓ | ↓ | ↓ | NM | Blood | Harphoush et al., [47]b | Mice (C57BL/6) | | 113 | ↑ | NM | ↓ | ↓ | ↓ | NM | Mammary tissue |
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MDA: malondialdehyde; ROS: reactive oxygen species; SOD: superoxide dismutase; CAT: catalase; GPx: glutathione peroxidase; ROS: scavenging capacity of reactive oxygen species; NM: not measured.
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