Comprehensive Analysis of Alteration Landscape and Its Clinical Significance of Mitochondrial Energy Metabolism Pathway-Related Genes in Lung Cancers

Figure 1

Mutation analysis of 188 mitochondrial energy metabolism pathway-related genes (MMRGs). (a) Mutated genes, change of base distribution. Different colors represent different base mutations. Blue means that base C is mutated to base A. Red means that base C is mutated to base T. Dark blue means that base C is mutated to base G. (b) Oncoplots of 188 MMRGs in lung cancer tissues. (c) Comparison of mutation frequency of different MMRGs in long survival group (>1000 days) vs. short survival group (<1000 days). (d) The survival of the ACOX3 mutant group was better than that of the wild-type group. (e) The survival of the OGDH mutant group was not significant than that of the wild group.

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