Research Article
A Novel Systematic Oxidative Stress Score Predicts the Prognosis of Patients with Operable Breast Cancer
Table 1
Clinical characteristics in the training set and validation set.
| Variables | Total () | Training set () | Validation set () | value | No. | % | No. | % | No. | % |
| Age | | | | | | | 0.252 | ≤60 | 1347 | 85.1 | 1003 | 84.5 | 344 | 86.9 | | >60 | 236 | 14.9 | 184 | 15.5 | 52 | 13.1 | | Multifocality | | | | | | | 0.927 | Yes | 39 | 2.5 | 29 | 2.4 | 10 | 2.5 | | No | 1544 | 97.5 | 1158 | 97.6 | 386 | 97.5 | | Histological grade | | | | | | | 0.180 | I | 108 | 6.8 | 89 | 7.5 | 19 | 4.8 | | II | 903 | 57.0 | 671 | 56.5 | 232 | 58.6 | | III | 572 | 36.2 | 427 | 36.0 | 145 | 36.6 | | VCE | | | | | | | 0.307 | Yes | 558 | 35.2 | 410 | 34.5 | 148 | 37.4 | | No | 1025 | 64.8 | 777 | 65.5 | 248 | 62.6 | | T stage | | | | | | | 0.371 | T1 | 717 | 45.3 | 549 | 46.2 | 168 | 42.4 | | T2 | 760 | 48.0 | 555 | 46.8 | 205 | 51.8 | | T3 | 60 | 3.8 | 47 | 4.0 | 13 | 3.3 | | T4 | 46 | 2.9 | 36 | 3.0 | 10 | 2.5 | | N stage | | | | | | | 0.248 | N0 | 828 | 52.3 | 630 | 53.1 | 198 | 50.0 | | N1 | 402 | 25.4 | 298 | 25.1 | 104 | 26.3 | | N2 | 207 | 13.1 | 145 | 12.2 | 62 | 15.7 | | N3 | 146 | 9.2 | 114 | 9.6 | 32 | 8.0 | | TNM stage | | | | | | | 0.263 | Stage I | 438 | 27.7 | 341 | 28.7 | 97 | 24.5 | | Stage II | 744 | 47.0 | 549 | 46.3 | 195 | 49.2 | | Stage III | 401 | 25.3 | 297 | 25.0 | 104 | 26.3 | | IHC subtype | | | | | | | 0.155 | Luminal A | 328 | 20.7 | 252 | 21.3 | 76 | 19.2 | | Luminal B | 883 | 55.8 | 645 | 54.3 | 238 | 60.1 | | HER2+ | 184 | 11.6 | 139 | 11.7 | 45 | 11.4 | | TNBC | 188 | 11.9 | 151 | 12.7 | 37 | 9.3 | | CRE (μmol/L) | | | | | | | 0.544 | <59.30 | 963 | 60.8 | 717 | 60.4 | 246 | 62.1 | | ≥59.30 | 620 | 39.2 | 470 | 39.6 | 150 | 37.9 | | DBIL (μmol/L) | | | | | | | 0.326 | <2.20 | 393 | 24.8 | 302 | 25.4 | 91 | 23.0 | | ≥2.20 | 1190 | 75.2 | 885 | 74.6 | 305 | 77.0 | | TBIL (μmol/L) | | | | | | | 0.262 | <13.80 | 1270 | 80.2 | 960 | 80.9 | 310 | 21.7 | | ≥13.80 | 313 | 19.8 | 227 | 19.1 | 86 | 78.3 | | LDH (U/L) | | | | | | | 0.732 | <205.70 | 1424 | 90.0 | 1066 | 89.8 | 358 | 90.4 | | ≥205.70 | 159 | 10.0 | 121 | 10.2 | 38 | 9.6 | | UA (μmol/L) | | | | | | | 0.357 | <255.20 | 408 | 25.8 | 299 | 25.2 | 109 | 27.5 | | ≥255.20 | 1175 | 74.2 | 888 | 74.8 | 287 | 72.5 | | BUN (mmol/L) | | | | | | | 0.466 | <6.29 | 1424 | 90.0 | 1064 | 89.6 | 360 | 90.9 | | ≥6.29 | 159 | 10.0 | 123 | 10.4 | 36 | 9.1 | | ALB (g/L) | | | | | | | 0.966 | <43.00 | 830 | 52.4 | 622 | 52.4 | 208 | 52.5 | | ≥43.00 | 753 | 47.6 | 565 | 47.6 | 188 | 47.5 | | CRP (mg/L) | | | | | | | 0.807 | <3.78 | 1361 | 86.0 | 1022 | 86.1 | 339 | 85.6 | | ≥3.78 | 222 | 14.0 | 165 | 13.9 | 57 | 14.4 | |
|
|