Protective Effects of the Soluble Receptor for Advanced Glycation End-Products on Pyroptosis during Myocardial Ischemia-Reperfusion

<div>Effects of sRAGE on pyroptosis in the myocardium following myocardial ischemia-reperfusion injury. (a) Representative immunohistochemical image of pyroptosis-associated proteins in myocardium, including NLRP3, caspase-1, GSDMD, IL-1<i>β</i>, and IL-18. The target protein is shown in brown, indicating pyroptosis-positive cardiomyocyte. The scale bar is 10 <i>μ</i>m. (b) Quantitative statistics of immunohistochemical images is shown above. 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Oxidative Medicine and Cellular Longevity

fig3

Figure 3

Figure 3: Protective Effects of the Soluble Receptor for Advanced Glycation End-Products on Pyroptosis during Myocardial Ischemia-Reperfusion 