Protective Effects of the Soluble Receptor for Advanced Glycation End-Products on Pyroptosis during Myocardial Ischemia-Reperfusion

<div>Effects of sRAGE on the transcription of IL-1<i>β</i> mRNA and IL-18 mRNA in primary cultured cardiomyocytes following ischemia-reperfusion injury. I/R groups were subjected to ischemia for 2 hours and reperfusion for 2 hours. (a) Quantitative RT-PCR of interleukin-1<i>β</i> mRNA expression in cardiomyocytes. (b) Quantitative RT-PCR of interleukin-18 mRNA expression in cardiomyocytes. <i>β</i>-Actin was used as the reference gene. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Protective Effects of the Soluble Receptor for Advanced Glycation End-Products on Pyroptosis during Myocardial Ischemia-Reperfusion 