Research Article
Bortezomib Rescues Ovariectomy-Induced Bone Loss via SMURF-Mediated Ubiquitination Pathway
Figure 4
The effect of bortezomib on the radiographic bone loss in OVX mice. (a) Representative images of micro-CT reconstruction for coronal and cross-sectional plane of mice femurs. (b) Quantification of bone microstructure parameters including bone mineral density (BMD), the bone volume ratio (BV/TV, %), bone surface/volume ratio (BS/BV, mmā1), and trabecular number (Tb.N, mmā1). Values represent of six samples in each group () in micro-CT assays. Statistically significant differences are indicated by where or where between the indicated groups.
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