Research Article
Bortezomib Rescues Ovariectomy-Induced Bone Loss via SMURF-Mediated Ubiquitination Pathway
Figure 5
The effect of bortezomib on the histological bone loss in OVX mice. (a) Representative histological images of rat femurs stained by hematoxylin and eosin (H&E), tartrate-resistant acid phosphatase (TRAP), and OCN immunofluorescence staining. . (b) Quantification of bone microstructure parameters including Tb area. (c, d) The percentage of the number of TRAP- or OCN-positive cells. Values represent of six samples in each group () in histological staining assays. Statistically significant differences are indicated by where or where between the indicated groups.
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