Protective Effect of Honey and Propolis against Gentamicin-Induced Oxidative Stress and Hepatorenal Damages

Table 5

Comparison between kidney and liver oxidative/antioxidant status.

Parameter	Gent					Gent+PR
	Kidney		Liver			Kidney		Liver
	Effect	%A	Effect	%A		Effect	%B	Effect	%B
CAT	Decrease	40.31	Decrease	24.67^a	0.001	Increase	52.10	Increase	27.15^b	0.001
GSH	Decrease	57.80	Decrease	54.52^a	0.005	Increase	111.87	Increase	80.78^b	0.001
GPx	Decrease	38.43	Decrease	40.56^a	0.006	Increase	46.46	Increase	36.18^b	0.002
Proteins	Decrease	28.58	Decrease	39.44^a	0.002	Increase	37.53	Increase	53.27^b	0.001
MDA	Increase	80.27	Increase	38.27^a	0.001	Decrease	26.61	Decrease	18.87^b	0.009
Parameter	Gent+H					Gent+PR+H
	Kidney		Liver			Kidney		Liver
	Effect	%C	Effect	%C		Effect	%D	Effect	%D
CAT	Increase	32.36	Increase	23.58^c	0.001	Increase	58.29	Increase	29.32^d	0.001
GSH	Increase	99.00	Increase	87.31^c	0.003	Increase	122.54	Increase	97.80^d	0.001
GPx	Increase	34.65	Increase	31.56^c	0.002	Increase	35.79	Increase	50.18^d	0.001
Proteins	Increase	72.08	Increase	50.29^c	0.001	Increase	41.92	Increase	57.09^d	0.001
MDA	Decrease	23.82	Decrease	18.00	0.031	Decrease	29.21	Decrease	24.36	0.171

%A: percentage of changes from the control induced by GENT administration; %B: percentage of changes from the GENT caused by propolis administration: %C: percentage of changes from the GENT caused by honey administration; %D: percentage of changes from the GENT caused by propolis+honey administration. ^a: statistically significant as compared to the effect GENT on kidney oxidative parameters; ^b: statistically significant as compared to the effect GENT+PR on kidney oxidative parameters; ^c: statistically significant as compared to the effect GENT+H on kidney oxidative parameters; ^d: statistically significant as compared to the effect GENT+PR+H on kidney oxidative parameters.