Ghrelin Alleviates Endoplasmic Reticulum Stress in MC3T3E1 Cells by Inhibiting AMPK Phosphorylation

Figure 4

Incidence of apoptosis related to endoplasmic reticulum stress in different groups associated with TM. (a)–(d) represent the flow apoptotic patterns of the TM, , , and groups, respectively. (e) Histogram of the incidence of apoptosis in each group. GSK621 (10 μmol/L) pretreated for 3 h, and then ghrelin (10^-7 mol/L) was pretreated for 4 h, followed by TM (1.5 μg/mL) treatment for 20 hours. Data represents the obtained from three separate experiments. indicates comparison with the TM group, indicates , ^# indicates comparison with the group, and ^### indicates .

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