Vascular Risk Factors, Imaging, and Outcomes in Transient Ischemic Attack/Ischemic Stroke Patients with Neuroimaging Evidence of Probable/Possible Cerebral Amyloid Angiopathy
Table 1
Characteristics of TIA/ischemic stroke patients with neuroimaging evidence of probable/possible CAA pattern.
Characteristic
All patients ()
CAA pattern ()
Non-CAA pattern ()
value
Age, mean (SD), y
66.5 (7.6)
67.8 (7.7)
66.2 (7.5)
0.001
Sex (female), No., %
490 (30.3%)
95 (32.7%)
395 (29.7)
0.33
BMI, mean (SD)
24.8 (3.2)
24.9 (3.2)
24.8 (3.2)
0.52
HTN No., %
1045 (64.5%)
212 (72.9%)
833 (62.7%)
0.001
DM No., %
387 (23.9%)
65 (22.3%)
322 (24.2%)
0.49
AF No., %
111 (6.9%)
29 (10.0%)
82 (6.2%)
0.02
Hyperlipidemia No., %
148 (9.1%)
23 (7.9%)
125 (9.4%)
0.42
Coronary artery disease No., %
11 (0.7%)
4 (1.4%)
7 (0.5%)
0.11
Prior ischemic stroke No., %
391 (24.1%)
91 (31.3%)
300 (22.6%)
0.002
Prior TIA No., %
47 (2.9%)
10 (3.4%)
37 (2.8%)
0.83
Current smoking No., %
505 (31.2%)
86 (29.6%)
419 (31.5%)
0.51
Alcohol No., %
239 (14.8%)
32 (11.0%)
207 (15.6%)
0.046
Education level No., %
0.56
>high school
118 (7.3%)
22 (7.6%)
96 (7.2%)
High school
344 (21.2%)
55 (18.9%)
289 (21.8%)
<high school
1158 (71.5%)
241 (73.5%)
944 (71.0%)
Initial mRS, mean (SD)
1.8 (1.3)
1.8 (1.3)
1.8 (1.3)
0.44
Initial MoCA, mean (SD)
19.2 (5.3)
18.9 (5.4)
19.3 (5.3)
0.24
Glucose mean (IQR), mg/dLb
6.3 (2.4)
6.1 (2.4)
6.4 (2.4)
0.03
Hgb g/L c
140.6 (16.2)
141.1 (16.6)
140.5 (16.1)
0.50
Plt 109/Ld
206.0 (56.8)
199.0 (58.7)
207.5 (56.3)
0.06
3 m MoCAe
22.1 (5.0)
21.4 (5.2)
22.3 (4.9)
0.03
12 m MoCAf
22.4 (4.9)
22.3 (4.7)
22.4 (5.0)
0.85
Abbreviations: CAA: cerebral amyloid angiopathy; BMI: body mass index; HTN: hypertension; DM: diabetes; AF: atrial fibrillation; TIA: transient ischemic attack; mRS: modified Rankin Scale; MoCA: Montreal Cognitive Assessment; Hgb: hemoglobin; Plt: platelet count. bData were missing for 227 patients. cData were missing for 9 patients. dData were missing for 12 patients. eData were missing for 233 patients. fData were missing for 724 patients.
