Research Article

TRPV1 Channel Activated by the PGE2/EP4 Pathway Mediates Spinal Hypersensitivity in a Mouse Model of Vertebral Endplate Degeneration

Table 2

Summary of current clamp properties of DRG neurons.

Current clamp propertiesSham+vehicleLSI+vehicleLSI+L161982
MeanSDMeanSDMeanSD

Input resistance (MΩ)520.91154.5520521.60153.0420497.21172.5620
Capacitance (pF)22.324.882022.464.922023.503.9620
RMP (mV)-59.007.5720-58.506.6420-58.657.3920
AP amplitude (mV)112.909.9420114.4310.0320113.206.6020
Threshold (pA, ramp protocol)470.00134.5414204.2681.7719351.38#71.4516

vs. sham+vehicle group, # vs. LSI+vehicle group.