Research Article
TRPV1 Channel Activated by the PGE2/EP4 Pathway Mediates Spinal Hypersensitivity in a Mouse Model of Vertebral Endplate Degeneration
Table 2
Summary of current clamp properties of DRG neurons.
| Current clamp properties | Sham+vehicle | LSI+vehicle | LSI+L161982 | Mean | SD | | Mean | SD | | Mean | SD | |
| Input resistance (MΩ) | 520.91 | 154.55 | 20 | 521.60 | 153.04 | 20 | 497.21 | 172.56 | 20 | Capacitance (pF) | 22.32 | 4.88 | 20 | 22.46 | 4.92 | 20 | 23.50 | 3.96 | 20 | RMP (mV) | -59.00 | 7.57 | 20 | -58.50 | 6.64 | 20 | -58.65 | 7.39 | 20 | AP amplitude (mV) | 112.90 | 9.94 | 20 | 114.43 | 10.03 | 20 | 113.20 | 6.60 | 20 | Threshold (pA, ramp protocol) | 470.00 | 134.54 | 14 | 204.26 | 81.77 | 19 | 351.38# | 71.45 | 16 |
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vs. sham+vehicle group, # vs. LSI+vehicle group. |