Recombinant High-Mobility Group Box 1 (rHMGB1) Promotes NRF2-Independent Mitochondrial Fusion through CXCR4/PSMB5-Mediated Drp1 Degradation in Endothelial Cells

Figure 2

rHMGB1 had no significant effect on the protein expression of PINK1, Mfn1, Mfn2, and Opa1. (a–d) Representative immunoblotting bands of PINK1, Mfn1, Mfn2, and Opa1 and the matching internal standard GAPDH. (e–h) The densitometric analysis of relative PINK1, Mfn1, Mfn2, and Opa1 expression referenced to respective matching GAPDH. GAPDH: glyceraldehyde-3-phosphate dehydrogenase. Data were expressed as the .

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