Oxidative Medicine and Cellular Longevity

Research Article

Mining Natural Products with Anticancer Biological Activity through a Systems Biology Approach

Table 2

Differentially expressed genes in diverse TCGA-derived cancers.
GeneTCGA cancer typeStatus
ATMOVDown
BADDLBC,THYMUp
BAK1PAADUp
BAXDLBC,GBM,PAAD,TGCT,THYMUp
BCL2CESC,OV,UCSDown
BCL2DLBC,LAML,THYMUp
BCL2L1PAADUp
BIRC5LAMLDown
BIRC5BLCA,BRCA,CESC,COAD,DLBC,GBM,LIHC,LUAD,LUSC,OV,PAAD,READ,SKCM,STAD,THYM,UCEC,UCSUp
CASP3DLBC,GBM,PAAD,THYMUp
CASP7DLBC,THYMUp
CASP9OVDown
CCNB1LAMLDown
CCNB1ACC,BLCA,BRCA,CESC,COAD,DLBC,GBM,LIHC,LUAD,LUSC,OV,PAAD,READ,SKCM,STAD,THYM,UCEC,UCSUp
CCND1LAMLDown
CCND1COAD,DLBC,KIRC,LGG,OV,PAAD,READ,STAD,THCA,THYMUp
CCND3PAADUp
CDC25CLAMLDown
CDC25CCESC,COAD,DLBC,GBM,OV,READ,STAD,THYM,UCEC,UCSUp
CDK1LAMLDown
CDK1ACC,BLCA,BRCA,CESC,COAD,DLBC,GBM,LIHC,LUAD,LUSC,OV,PAAD,READ,STAD,THYM,UCEC,UCSUp
CDK2DLBC,GBM,SKCM,THYMUp
CDK4DLBC,GBM,LGG,SARC,TGCT,THYMUp
CDKN1AOVDown
CDKN1AGBMUp
CHEK2DLBC,TGCT,THYMUp
CXCL8CESC,COAD,ESCA,GBM,HNSC,PAAD,READ,SKCM,STAD,UCECUp
E2F1BLCA,BRCA,CESC,COAD,DLBC,LIHC,OV,PAAD,READ,THYM,UCEC,UCSUp
HLA-DRB1DLBC,GBM,LAML,LGG,OV,PAAD,STAD,TGCT,THYMUp
JUNSKCMDown
MAPK1LAMLDown
MAPK3PAADUp
MAPK8THYMUp
MDM2DLBC,SARC,THYMUp
MMP2ACC,CESC,OV,SKCMDown
MMP2DLBC,GBM,LAML,LGG,PAAD,THYMUp
MMP9THYMDown
MMP9BLCA,BRCA,CESC,COAD,ESCA,GBM,HNSC,OV,PAAD,READ,SKCM,STAD,TGCT,THCA,UCEC,UCSUp
MTORTHYMUp
MYCCOAD,DLBC,GBM,LGG,READ,THYMUp
NFKB1THYMUp
NOS2COAD,READUp
PARP1DLBC,THYMUp
PIK3CDSKCMUp
PTGS2LAML,PAADUp
RB1GBM,THYMUp
SERPINE1KICH,OVDown
SERPINE1DLBC,ESCA,GBM,HNSC,PAADUp
SMAD3UCECDown
SMAD3THYMUp
TGFB1GBM,LGG,PAADUp
TIMP2BLCA,CESC,OV,UCECDown
TIMP2LAML,PAADUp
TNFSF10KICHDown
TNFSF10CESC,LAML,PAAD,TGCTUp
TP53DLBC,GBM,LAML,LGG,THYMUp
TRAF1OV,UCSDown
TRAF1DLBCUp
XIAPTHYMUp