Inositol Alleviates Pulmonary Fibrosis by Promoting Autophagy via Inhibiting the HIF-1α-SLUG Axis in Acute Respiratory Distress Syndrome

Figure 6

Inositol promoted autophagy, which blocked EMT by regulating SLUG expression. (a) SLUG, HIF-1α, N-cadherin, and E-cadherin expression in HPAEpiC cells treated with RAPA and 3-MA. (b) Beclin-1, LC3BI, LC3BII, and P62 expression in cells treated with RAPA and 3-MA; (c) LC3B expression was detected by immunofluorescence and DAPI was used to stain the nucleus, .

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