ROS: Basic Concepts, Sources, Cellular Signaling, and its Implications in Aging Pathways

Figure 2

ROS at optimal level control cell fate by redox signaling. The balance of pro-oxidants and antioxidants maintains ROS at a safe zone for the cell. However, both the reductive (excess of antioxidant activities) and the oxidative stress can lead the cell to death. In addition, proliferation, survival, inflammation, and metabolism are some features controlled by redox signaling.