Sepsis-Induced Brain Dysfunction: Pathogenesis, Diagnosis, and Treatment

Table 2

Suggested treatments to sepsis-induced brain dysfunction.

Therapies	Mechanism
Vagus nerve stimulation	Regulation inflammatory response to protect organs [74]
Antioxidant therapies	Reduces oxidative stress to improve brain function [74]
Glucocorticoids	Regulate the secretion of hormones and anti-inflammatory [144]
CNI-1493	Regulation neuroinflammation by inhibiting P38/MAPK signaling [145]
Hypothermia	Change antibiotic pharmacokinetics [146]
IDO	Influences neuroinflammation [147]
Rg1	Anti-inflammation, suppress apoptosis, and autophagic degradation [148]
CC16	Anti-inflammatory, antioxidant, regulation autophy [153]