Research Article
XPO1-Mediated EIF1AX Cytoplasmic Relocation Promotes Tumor Migration and Invasion in Endometrial Carcinoma
Figure 6
Lung metastases 5 weeks after injection of HEC1A cells in the mice that had received tail vein injection. (a) Ctrl group. (b) KD group. (c) KD + Esm group. (d) KD + NLSsm group. Scale bar: 100 μm. (e) The area of lung metastases were determined by ImageJ. One-way ANOVA: , ns: , . Bars indicate SD. Note: Ctrl group (empty vector plasmid), KD group (EIF1AX-shRNA), KD + Esm group (EIF1AX-shRNA+pcDNA3.1-EIF1AXsm), and KD + NLSsm group (EIF1AX-shRNA+pcDNA3.1-EIF1AXsm-SV40NLS).
(a) |
(b) |
(c) |
(d) |
(e) |