Research Article
XPO1-Mediated EIF1AX Cytoplasmic Relocation Promotes Tumor Migration and Invasion in Endometrial Carcinoma
Table 1
The relationship between cytoplasmic EIF1AX expression and clinicopathological features in endometrial carcinoma.
| Clinical parameters | | | Cytoplasmic EIF1AX | value | Negative (-) | Positive (+~++++) |
| Histological type | Endometrioid | 286 | 50 | 236 | <0.001 | Serous | 29 | 6 | 23 | | FIGO grade | Grade 1 | 140 | 42 | 98 | <0.001 | Grade 2 | 99 | 6 | 93 | | Grade 3 | 47 | 2 | 45 | | FIGO stage | I + II | 243 | 53 | 190 | 0.001 | III + IV | 72 | 3 | 69 | | Invasive depth | <1/2 | 176 | 38 | 138 | 0.046 | ≥1/2 | 139 | 18 | 121 | | Lymphovascular invasion | Negative | 222 | 41 | 181 | 0.620 | Positive | 93 | 15 | 78 | | Lymph node metastasis | Negative | 178 | 6 | 172 | 0.634 | Positive | 27 | 2 | 25 | | MELF pattern of invasion | Negative | 239 | 38 | 201 | 0.112 | Positive | 47 | 12 | 35 | | Ki67 index | Low expression (≤50%) | | 54 | 163 | <0.001 | High expression (>50%) | | 2 | 96 | |
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MELF: microcystic elongated and fragmented.
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