XPO1-Mediated EIF1AX Cytoplasmic Relocation Promotes Tumor Migration and Invasion in Endometrial Carcinoma

Table 1

The relationship between cytoplasmic EIF1AX expression and clinicopathological features in endometrial carcinoma.

Clinical parameters			Cytoplasmic EIF1AX		value
			Negative (-)	Positive (+~++++)
Histological type	Endometrioid	286	50	236	<0.001
	Serous	29	6	23
FIGO grade	Grade 1	140	42	98	<0.001
	Grade 2	99	6	93
	Grade 3	47	2	45
FIGO stage	I + II	243	53	190	0.001
	III + IV	72	3	69
Invasive depth	<1/2	176	38	138	0.046
	≥1/2	139	18	121
Lymphovascular invasion	Negative	222	41	181	0.620
	Positive	93	15	78
Lymph node metastasis	Negative	178	6	172	0.634
	Positive	27	2	25
MELF pattern of invasion	Negative	239	38	201	0.112
	Positive	47	12	35
Ki67 index	Low expression (≤50%)		54	163	<0.001
	High expression (>50%)		2	96

MELF: microcystic elongated and fragmented.