XPO1-Mediated EIF1AX Cytoplasmic Relocation Promotes Tumor Migration and Invasion in Endometrial Carcinoma

Table 3

Univariate and multivariate analyses of the cytoplasmic EIF1AX expression and clinical-pathological factors on survival.

Variables	Univariate		Multivariate
	HR (95% CI)		HR (95% CI)
Cytoplasmic EIF1AX expression (negative vs. positive)	26.313 (0.064-10778.959)	0.287
Cytoplasmic EIF1AX expression (low vs. high)	3.325 (1.134-9.746)	0.029
Histological type (endometroid vs. serous)	8.092 (2.790-23.470)	<0.001	5.416 (1.755-17.022)	0.003
Histological grade (low vs. high)	7.722 (2.173-27.442)	0.002
FIGO stage(I + II vs. III + IV)	6.112 (2.183-17.114)	0.001
Invasive depth (<1/2 vs. ≥1/2)	5.601 (1.780-17.627)	0.003
Lymphovascular invasion (no vs. yes)	2.034 (0.721-5.740)	0.180
Ki67 index (low vs. high)	7.179 (2.283-22.575)	0.001	5.252 (1.611-17.117)	0.006