Lysionotin Induces Ferroptosis to Suppress Development of Colorectal Cancer via Promoting Nrf2 Degradation

<div>Lip1 pretreatment abolished Lys-mediated suppression of CRC cells. Prior to the addition of 30 M of Lys, HCT116 and SW480 cells were pretreated with Lip1 at a concentration of 200 nM for six hours. The CCK-8 test and the clonogenic assay were used to determine the level of cell viability (b) and survival (c), respectively, 24 hours after Lys was administered. The Transwell test was used to ascertain the level of motility present in CRC cells (c, d). 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Lysionotin Induces Ferroptosis to Suppress Development of Colorectal Cancer via Promoting Nrf2 Degradation 