Anthocyanin Encapsulated Nanoparticles as a Pulmonary Delivery System

Figure 1

The experimental plan and the timeline of delivering anthocyanins via the respiratory route. (a) Preparation of HB-CMC nanoparticles by ionic gelation. (b) The methodology of delivering nanoparticles via nose-only exposure. The nose-only delivery devices consisted of an ultrasonic mesh nebulizer connected to an aerosol holding chamber connected to a perforated mouse holding chamber. (c) Timeline of pulmonary delivery of anthocyanins. Numbers (D1–D16) represent days from the beginning of the experiment. CMC: carboxymethyl chitosan; HB: haskap berry anthocyanin.

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