1,25(OH)₂D₃ Mitigates Oxidative Stress-Induced Damage to Nucleus Pulposus-Derived Mesenchymal Stem Cells through PI3K/Akt Pathway

Figure 4

1,25(OH)₂D₃ improves H₂O₂-induced nucleus pulposus-derived mesenchymal stem cell (NPMSC) apoptosis. (a) Annexin V/PI staining flow cytometry results of NPMSCs. (b) Quantitative analysis of the apoptotic rate of NPMSCs. (c) TUNEL assay results of NPMSCs ( μm;  μm). (d) Quantitative analysis of TUNEL-staining positive cells. All data are the . compared with the control group; compared with the H₂O₂ group; ^&& compared with the 1,25(OH)₂D₃ group. LY: LY294002 group.

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