Sanguinarine-Chelerythrine Fraction of Coptis chinensis Exerts Anti-inflammatory Activity in Carrageenan Paw Oedema Test in Rats and Reveals Reduced Gastrotoxicity

Figure 5

Macroscopic examination of the gastric mucosa. Experimental groups (): (a) group receiving investigational alkaloid fraction of C. chinensis containing sanguinarine and chelerythrine 1 mg/kg (SC₁); (b) group receiving investigational alkaloid fraction of C. chinensis containing sanguinarine and chelerythrine 5 mg/kg (SC₅); (c) group receiving investigational alkaloid fraction of C. chinensis containing sanguinarine and chelerythrine 10 mg/kg (SC₁₀); (d) group receiving indomethacin 10 mg/kg (IND); (e) positive control group (CAR); (f) negative control group (CON).

(a)

(b)

(c)

(d)

(e)

(f)