Sanguinarine-Chelerythrine Fraction of Coptis chinensis Exerts Anti-inflammatory Activity in Carrageenan Paw Oedema Test in Rats and Reveals Reduced Gastrotoxicity

Table 3

The impact of investigational alkaloid fraction of C. chinensis containing sanguinarine and chelerythrine on pH of gastric juice. Indomethacin was used as a reference drug.

Group	pH
CON
CAR
IND
SC1	^##
SC5
SC10

CON: negative control group; CAR: positive control group; IND: group receiving indomethacin 10 mg/kg; SC₁, SC₅, and SC₁₀ : groups receiving investigational alkaloid fraction of C. chinensis containing sanguinarine and chelerythrine (1, 5, and 10 mg/kg, respectively). Data are presented as the . ^##vs. IND.