The Effect of Allograft Inflammatory Factor-1 on Inflammation, Oxidative Stress, and Autophagy via miR-34a/ATG4B Pathway in Diabetic Kidney Disease

Table 1

Physiological indicators and inflammatory factors in serum of DKD patients.

Clinical parameters	Control ()	Group 1 ()	Group 2 ()	Group 3 ()
FPG (mmol/L)
FINS (μmol/L)
Total cholesterol (mmol/L)
Triglycerides (mmol/L)
Serum creatinine (mg/L)
BUN (mmol/L)
eGFR (ml/min/1.73m^2)
AST (unit/g)
ALT (unit/L)
Albumin (g/L)
AIF-1 (pg/mL)			^#	^#
miR-34a (fold)			^#	^#
NLRP3 (ng/ml)			^#	^#
ATG4B (ng/ml)			^#	^#
IL-1β (pg/mL)			^#	^#
IL-18 (pg/mL)			^#	^#

Control: healthy people; FPG: fasting plasma glucose; FINS: fasting insulin; BUN: urea nitrogen; eGFR: estimated glomerular infiltration rate; AST: aspartate aminotransferase; ALT: alanine transaminase; AIF-1: allograft inflammatory factor-1; miR-34a: microRNA 34a; ATG4B: autophagy related 4 homolog B; NLRP3: NOD-like receptor thermal protein domain associated protein 3; IL-1β: interleukin 1β; IL-18: interleukin 18; Group 1: ; Group 2: ; Group 3: normal control group; versus control, , #.