The Effect of Allograft Inflammatory Factor-1 on Inflammation, Oxidative Stress, and Autophagy via miR-34a/ATG4B Pathway in Diabetic Kidney Disease

Table 3

The levels of biochemical indexes and inflammatory factors in db/db mice for 4-12 weeks ().

Parameters	db/m mice	db/db mice
	4-12 weeks	4 weeks	8 weeks	12 weeks
Blood glucose (mmol/L)			^#	^#
Total cholesterol (mmol/L)				^#
Triglycerides (mmol/L)				^#
Serum creatinine (mg/L)				^#
BUN (mmol/L)
UACR (μg/mg)			^#	^#
AST (unit/L)
ALT (unit/L)
Total protein (g/dL)
AIF-1 (pg/mL)			^#	^#
miR-34a (fold)			^#	^#
NLRP3 (ng/ml)			^#	^#
ATG4B (ng/ml)			^#	^#
IL-1β (pg/mL)			^#	^#
IL-18 (pg/mL)			^#	^#

BUN: urea nitrogen; UACR: urea albumin creatinine ratio; AST: aspartate aminotransferase; ALT: alanine transaminase; AIF-1: allograft inflammatory factor-1; miR-34a: microRNA 34a; ATG4B: autophagy related 4 homolog B; NLRP3: NOD-like receptor thermal protein domain associated protein 3; IL-1β: interleukin 1β; IL-18: interleukin 18; versus db/m mice, , #.