The Effect of Allograft Inflammatory Factor-1 on Inflammation, Oxidative Stress, and Autophagy via miR-34a/ATG4B Pathway in Diabetic Kidney Disease

Table 4

The levels of AIF-1, miR-34a, ATG4B, and inflammatory factors in AIF-1^+/+ and AIF-1^-/- mice for 12 weeks ().

Parameters	12 weeks
	Wild mice	AIF-1^+/+ mice	AIF-1^-/- mice
Blood glucose (mmol/L)
Total cholesterol (mmol/L)
Triglycerides (mmol/L)
Serum creatinine (mg/L)
BUN (mmol/L)
UACR (μg/mg)			^#
AST (unit/L)
ALT (unit/L)
Total protein (g/dL)
AIF-1 (pg/mL)			^#
miR-34a (fold)			^#
NLRP3 (ng/ml)			^#
ATG4B (ng/ml)			^#
IL-1β (pg/mL)			^#
IL-18 (pg/mL)			^#

BUN: urea nitrogen; UACR: urea albumin creatinine ratio; AST: aspartate aminotransferase; ALT: alanine transaminase; AIF-1: allograft inflammatory factor-1; miR-34a: microRNA 34a; ATG4B: autophagy related 4 homolog B; NLRP3: NOD-like receptor thermal protein domain associated protein 3; IL-1β: interleukin 1β; IL-18: interleukin 18; versus wild mice, , #.