Aberrant Expression of Mitochondrial SAM Transporter SLC25A26 Impairs Oocyte Maturation and Early Development in Mice

Figure 4

SLC25A26 overexpression disrupts mitochondrial redistribution, membrane potential, and ATP content in oocyte. (a) Representative images of mitochondrial distribution in control and SLC25A26-OE oocytes. Oocytes were stained with Mito-Tracker Red to show mitochondria. Scale  μm. (b) Each mitochondrial distribution pattern rate was recorded in in control and SLC25A26-OE oocytes. and . (c) Mitochondrial membrane potential () was detected by JC-1 staining in control and SLC25A26-OE oocytes (red, high ΔΨm; green, low ΔΨm). Scale  μm. (d) The ratio of red to green fluorescence intensity was calculated in control and SLC25A26-OE oocytes. (e) ATP levels were measured in control and SLC25A26-OE oocytes. Data are presented as the .

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