Aberrant Expression of Mitochondrial SAM Transporter SLC25A26 Impairs Oocyte Maturation and Early Development in Mice

Table 1

Misregulated genes upon SLC25A26 overexpression in mouse oocytes.

Gene symbols	Chr	Description and function (source: UniProt)
C1qc	4	Complement C1q subcomponent subunit C. Complement activation, classical pathway source, and innate immune response [51].
Ccl4	11	Chemokine (C-C motif) ligand 4. Cytokine, chemotaxis, and inflammatory response [52].
Ctss	3	Cathepsin S. Antigen processing and presentation of exogenous peptide antigen via MHC class II Source [53].
Tmsb4x	X	Thymosin beta-4. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization [54].
Scimp	11	SLP adaptor and CSK interacting membrane protein. Lipid tetraspanin-associated transmembrane adapter/mediator that acts as a scaffold for Src family kinases and other signaling proteins in immune cells [55].
Pramel38	5	PRAME-like 38. Negative regulation of apoptotic process, cell differentiation and transcription, and DNA-templated. Positive regulation of cell population proliferation. Source: InterPro.
Mt-Cytb	MT	Mitochondrially encoded cytochrome b. Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain [56].
E330014E10Rik	5	RIKEN cDNA E330014E10 gene. Negative regulation of apoptotic process, cell differentiation and transcription, and DNA-templated. Positive regulation of cell population proliferation. Source: InterPro.
Pomc	12	Proopiomelanocortin. A polypeptide hormone precursor yielding several biologically active peptides involved in different cellular functions.
Prl	13	Prolactin acts primarily on the mammary gland by promoting lactation.
Nnat	2	Neuronatin participates in brain development.
Gh	11	Growth hormone is involved in growth control.