Research Article

Gliclazide in Binary and Ternary Systems Improves Physicochemical Properties, Bioactivity, and Antioxidant Activity

Table 3

Hardness and percent friability of tablets prepared in different ratio.

SamplesWeight variation (mg)Hardness (kg/cm2)Percent friability

Control (gliclazide)
PM 1 : 1
PM 1 : 2.5
PM 1 : 4
PM 1 : 9
PM 1 : 1 : 0.27
PM 1 : 1 : 1
PM 1 : 2.5 : 0.27
PM 1 : 3.6 : 3.6
PM 1 : 4 : 1
PM 1 : 9 : 1
SE 1 : 1
SE 1 : 2.5
SE 1 : 4
SE 1 : 9
SE 1 : 1 : 0.27
SE 1 : 1 : 1
SE 1 : 2.5 : 0.27
SE 1 : 3.6 : 3.6
SE 1 : 4 : 1
SE 1 : 9 : 1

PM: prepared by physical mixing method; SE: prepared by solvent evaporation method.