Research Article
Gliclazide in Binary and Ternary Systems Improves Physicochemical Properties, Bioactivity, and Antioxidant Activity
Table 3
Hardness and percent friability of tablets prepared in different ratio.
| Samples | Weight variation (mg) | Hardness (kg/cm2) | Percent friability |
| Control (gliclazide) | | | | PM 1 : 1 | | | | PM 1 : 2.5 | | | | PM 1 : 4 | | | | PM 1 : 9 | | | | PM 1 : 1 : 0.27 | | | | PM 1 : 1 : 1 | | | | PM 1 : 2.5 : 0.27 | | | | PM 1 : 3.6 : 3.6 | | | | PM 1 : 4 : 1 | | | | PM 1 : 9 : 1 | | | | SE 1 : 1 | | | | SE 1 : 2.5 | | | | SE 1 : 4 | | | | SE 1 : 9 | | | | SE 1 : 1 : 0.27 | | | | SE 1 : 1 : 1 | | | | SE 1 : 2.5 : 0.27 | | | | SE 1 : 3.6 : 3.6 | | | | SE 1 : 4 : 1 | | | | SE 1 : 9 : 1 | | | |
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PM: prepared by physical mixing method; SE: prepared by solvent evaporation method.
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