Bovine Lactoferrin Induces Cell Death in Human Prostate Cancer Cells

Figure 3

bLf causes morphological changes in the DU-145 cell line. To verify the effects of bLf, selected images were taken using an EVOS microscope. (a) DU-145 cells were treated for 24 and 48 h with apo-bLf and holo-bLf at 8 and 16 mg/mL. (b) Zoom in of 8 mg/mL after 48 h treatment showing intracellular granules. The control cell received only a culture medium. The white bars represent a distance of 100 μm. Arrowheads indicate stretched morphology.