Research Article

Bovine Lactoferrin Induces Cell Death in Human Prostate Cancer Cells

Table 1

bLf modulates cell cycle of DU-145 cell line. The table below shows the percentage of cells in each cell cycle phase determined by flow cytometry. This table represents three different experiments expressed as . The one-way ANOVA test compared significant differences between untreated and treated cells with the Bonferroni post hoc test.

24 h treatment48 h treatment
G0/G1 (%)S (%)G2/M (%)G0/G1 (%)S (%)G2/M (%)

Control
Apo-bLf 2 mg/mL
Apo-bLf 4 mg/mL
Apo-bLf 8 mg/mL
Apo-bLf 16 mg/mL
Holo-bLf 2 mg/mL
Holo-bLf 4 mg/mL
Holo-bLf 8 mg/mL
Holo-bLf 16 mg/mL

Different letters indicate statistical difference compared to control (a; b).