NRF3 Decreases during Melanoma Carcinogenesis and Is an Independent Prognostic Marker in Melanoma

Table 1

Patient cohort.

Total number of patients	143
Age median (years)	60
Samples per diagnosis
Compound naevus	20
Intradermal naevus	22
Dysplastic naevus	39
Nodular melanoma	30
Superficially spreading melanoma	29
Acral melanoma	8
Metastasis	51
Number of patients with malignant melanoma	63
Median age (years)	70
Gender
Males	44
Females	19
Breslow’s thickness
≤1 mm	11
1–1.9 mm	14
2–3.9 mm	13
>4 mm	29
Breslow mean (mm)	4.98
Breslow median (mm)	3.50
Clark level
I-II	2
III-V	65
Ulceration
Yes	26
No ulceration (one case not defined)	41
Mitotic activity
Low	38
High	29
Tumour-infiltrating lymphocytes
Absence	28
Nonbrisk	30
Brisk	9
Pigmentation
None to average	42
Abundant	25
Melanoma location
Head or neck	19
Upper limb	10
Body	24
Lower limb	14
N
0	38
1	8
2	11
3	10