Activation of Sirtuin-1 by Pinocembrin Treatment Contributes to Reduced Early Brain Injury after Subarachnoid Hemorrhage

Figure 2

Pinocembrin upregulated SIRT1 activation and improved histological outcomes after SAH. (a) Western blotting was used to analyze SIRT1 expression. (b) Pinocembrin increased SIRT1 expression after SAH. (c) Representative photomicrographs of SIRT1 staining in brain tissue at 24 h post-SAH. (d) Pinocembrin resulted in enhanced SIRT1 staining at 24 h post-SAH. (e) Representative photomicrographs of cresyl violet-stained images. (f) Pinocembrin improved neuronal survival at 72 h post-SAH. Scale  μm. Values were presented as , per group. .

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