STAT6/VDR Axis Mitigates Lung Inflammatory Injury by Promoting Nrf2 Signaling Pathway

<div>STAT6 deficiency exacerbated particle caused lung oxidative injury. (a) Representative photographs of lung tissue STAT6 staining from Stat6<sup>+/+</sup> and Stat6<sup>-/-</sup> mice. (b) Representative H&amp;E-stained lung sections (black arrows indicated pulmonary nodule, and infiltration of inflammatory cells was magnified at the below). (c) The protein content of BALF from the indicated group was measured. 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(d) IHC staining of 8-oxo-dG in lung tissue sections from the indicated groups was performed. (e) TUNEL staining of lung tissue. Representative images from each group were shown.</div>

Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: STAT6/VDR Axis Mitigates Lung Inflammatory Injury by Promoting Nrf2 Signaling Pathway 