Ketone Body β-Hydroxybutyrate Prevents Myocardial Oxidative Stress in Septic Cardiomyopathy

Figure 6

Schematic illustration of the working model for this study. β-OHB is an HDAC inhibitor that enhances histone acetylation to activate the antioxidant FoxO3a/MT2 pathway for preventing ROS production from protecting the mitochondria in septic cardiomyopathy.