Fetal Zone Steroids Show Discrete Effects on Hyperoxia-Induced Attenuation of Migration in Cultured Oligodendrocyte Progenitor Cells

Table 2

Impact of steroids on OPC migration and protein levels upon hyperoxia.

	Control	DHEA	16α-OH-DHEA	Adiol
Migration	↓-	↑+	↓-	↑+
Cofilin	↓-	↑(+)	n.a.	↑(+)
P-cofilin	↑+	n.a.	n.a.	↓-
LIMK	↑+	↓-	↓-	↓-
P-LIMK	↑+	↓-	↓-	↓-
TESK	↑+	↓-	↑+	↓-
Chronophin	↑+	↑+	↓-	↓-

Hyperoxic control has been considered as the baseline, and the effects of the steroids on migration and protein levels under hyperoxic conditions have been interpreted accordingly. Furthermore, the effect of hyperoxia compared to the normoxic control is indicated. The abbreviation “n.a.” represents “not altered” and “(+)” represents a trend towards increase.