Research Article

The Gender-Specific Interaction of DVL3 and GSK3β Polymorphisms on Major Depressive Disorder Susceptibility in a Chinese Han Population: A Case-Control Study

Table 9

Analysis of association between DVL3/GSK3β haplotype and MDD in different gender subgroups.

HaplotypeFemaleMale
CaseControlCaseControl

DVL3
C-C0.4590.5338.0830.0310.4470.5051.5810.606
T-A0.5160.4516.3040.0950.5290.4842.5020.814
GSK3β
G-G-A0.4590.55714.599<0.010.5010.5572.3850.619
A-A-G0.3850.30111.6550.0020.3490.3011.9950.729
A-A-A0.0590.0393.0560.5630.0650.0480.9830.946
G-A-G0.0390.0430.1891.0000.0400.0280.7800.966

Note: DVL3: rs1709642-rs1969253; GSK3β: rs334558-rs6438552-rs2199503.