PGF2α-FP Receptor Ameliorates Senescence of VSMCs in Vascular Remodeling by Src/PAI-1 Signal Pathway

Figure 1

The expression of FP receptor was increased in the aorta of aging mice, and FP receptor gene silencing could delay cell senescence process in the aorta of aging mice. (a) Immunohistochemical staining and analysis of FP receptor. (b) Representative Western blot and analysis of FP receptor. (c) Representative SA-β-Gal staining with the aorta from the mice (scale bar: 20 μm). (d) Representative Western blot and analysis of P16, P21, and P53.

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