6-Gingerol Alleviates Ferroptosis and Inflammation of Diabetic Cardiomyopathy via the Nrf2/HO-1 Pathway

Figure 4

6-Gingerol inhibits ferroptosis and inflammation in vitro. (a) Cell proliferation of H9c2 in different concentrations of 6-G was determined by a CCK-8 cell proliferation assay. (b) Representative blots of FACL4 and GPX4 in H9c2 cells (). (c, d) Histograms showing the fold change of FACL4 and GPX4. Relative mRNA expression of FACL4 (e), GPX4 (f), IL-1β (g), IL-6 (h), and TNF-α (i) (). All data for protein and mRNA levels were normalized to GAPDH before quantitative analysis. All values are expressed as . ^#, compared with the CON or 6-G group; , compared with the HG group.

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