Research Article
6-Gingerol Alleviates Ferroptosis and Inflammation of Diabetic Cardiomyopathy via the Nrf2/HO-1 Pathway
Figure 5
6-G upregulates the expression of Nrf2 and HO-1 in DCM both in vivo and in vitro. (a) Representative blots for Nrf2 and HO-1 in the mouse heart (). (b) Representative blots of Nrf2 and HO-1 in H9c2 cells (). (c, d) Histograms showing the fold change of Nrf2 and HO-1 in mouse hearts. (e, f) Relative mRNA expression of Nrf2 and HO-1 in mouse hearts (). (g, h) Histograms showing the fold change of Nrf2 and HO-1 in H9c2 cells. (i, j) Relative mRNA expression of Nrf2 and HO-1 in H9c2 cells (). All data for proteins and mRNA was normalized to GAPDH before relative quantitative analysis. All values are expressed as . #, compared with the CON or 6-G group; , compared with the HG or STZ group.
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