The Effects of RBP4 and Vitamin D on the Proliferation and Migration of Vascular Smooth Muscle Cells via the JAK2/STAT3 Signaling Pathway

Figure 4

Representative HE staining of thoracic aortas. (a) 10x; scale bar, 200 μm. (b) 20x; scale bar, 50 μm. (A) There were no obvious changes in the structure of aortas in the group NC. (B) The intima became thicker and the VSMCs arranged disorderly in group DM. (C) A large number of VSMCs migrated and proliferated and distinct plaques with abundant lipids and calcification formed in the aortas of the rats in group DAS. (D, E) There were small formations of plagues and calcification on the walls of aortas in the groups VDAS-1 and VDAS-2. (F) The intima was smooth and VSMCs arranged neatly in the group VDAS-3.

(a)

(b)