Research Article

The Effects of RBP4 and Vitamin D on the Proliferation and Migration of Vascular Smooth Muscle Cells via the JAK2/STAT3 Signaling Pathway

Table 2

Biochemical parameters of rats in different groups.

NC ()DM ()DAS ()VDAS-1 ()VDAS-2 ()VDAS-3 ()

Weight (g)aa,ba,ca,b,c,da,b,c,d46.973≤0.001
MT (μm)aa,ba,ba,b,c,a,b,c,d,e59.350≤0.001
LD (mm)a,ba,ba,b,c,da,b,c,d,e24.540≤0.001
LDL-caa,ba,ba,ba,b,c,d,e66.648≤0.001
TGa9a,ba,b,ca,b,da,b,c,e177.841≤0.001
TCaa,ba,b,ca,b,ca,c,d,e66.424≤0.001
HDL-caa,ba,b,ca,ba,b,c,d,e83.240≤0.001
HbA1Caa,ba,ba,c,da,c,d121.350≤0.001
FPGaaaa,b,c,da,b,c,d160.800≤0.001
FINSaa,ba,ba,ba,b,c,d,e117.934≤0.001
RBP4aa,ba,b,ca,b,ca,c,d,e127.386≤0.001
HOMA-IRaa,ba,ba,b,c,da,c,d,e182.703≤0.001
25(OH)Daa,ba,b,ca,b,c,da,b,c,d,e656.205≤0.001
ISI-aa,ba,ba,b,c,da,c,d,e475.785≤0.001

a vs. the NC group, b vs. the DM group, c vs. the DAS group, d vs. the VDAS-1 group, and e vs. VDAS-2 group. NC: control group; DM: diabetes without macrovascular disease group; DAS: diabetic atherosclerosis group; VDAS-1: Diabetic atherosclerosis group treated with vitamin D 0.075 μg kg-1 d-1; VDAS-2: diabetic atherosclerosis group treated with vitamin D 0.15 μg kg-1μd-1; VDAS-3: diabetic atherosclerosis group treated with vitamin D 0.3 μg kg-1 d-1; MT: the media thickness of the artery; LD: lumen diameter; LDL-c: low-density lipoprotein cholesterol; TG: triglycerides; TC: total cholesterol; HDL-c: high-density lipoprotein cholesterol; HbA1C: hemoglobin A1c; FPG: fasting plasma glucose; FINS: fasting insulin; RBP4: retinol binding protein 4; HOMA-IR: homeostasis model assessment of insulin resistance; ISI: insulin sensitivity index.