Association of the Combined Effects between Insulin-Like Growth Factor-1 Gene Polymorphisms and Negative Life Events with Major Depressive Disorder among Chinese population in the Context of Oxidative Stress

Table 3

Association of IGF-1 genotypes and alleles on the risk of MDD.

SNP	Group	Genotype frequencies			( value)	Allele frequencies		( value)	OR (95% CI)
		C/C	T/C	T/T		C	T
rs972936	Case	144 (34.3%)	205 (48.8%)	71 (16.9%)	26.39 (<0.001)	493 (58.7%)	347 (41.3%)	18.53 (<0.001)	1.53 (1.26-1.85)
	Control	120 (28.6%)	165 (39.3%)	135 (32.1%)		405 (48.2%)	435 (51.8%)
rs978458	Case	69 (16.4%)	294 (70.0%)	57 (13.6%)	137.51 (<0.001)	432 (51.4%)	408 (48.6%)	42.30 (<0.001)	1.92 (1.58-2.34)
	Control	215 (51.2%)	133 (31.7%)	72 (17.1%)		563 (67.0%)	277 (33.0%)