The Effects of In Utero Fetal Hypoxia and Creatine Treatment on Mitochondrial Function in the Late Gestation Fetal Sheep Brain

Figure 5

Mitochondrial density and cytochrome c release. The ratio of mitochondrial cytochrome c to nonmitochondrial cytochrome c in the cortical grey matter (a), subcortical white matter (b), hippocampus CA1-CA3 (c), and dentate gyrus (d) regions. Mitochondrial density measured as % of COXIV intensity per tissue area in cortical grey matter (e), subcortical white matter (f), hippocampus CA1-CA3 (g), and dentate gyrus (h). Saline-control (), creatine-control (), saline-UCO (), and creatine-UCO (). Statistical analysis, two-Way ANOVA, and Tukey’s multiple comparison. Data are shown as analyzed by two-Way ANOVA, and Tukey's multiple comparison. Significance denoted by refers to .

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