Association between Arsenic Level, Gene Expression in Asian Population, and In Vitro Carcinogenic Bladder Tumor

Figure 1

Sample distribution of gene expression profiles: (a) Data1; (B) Data2. The partial least squares discriminant analysis (PLS-DA) plot showing clusters of samples based on similarity. The first two components of PLS-DA (PC1 and PC2) of gene expression profile and overall variance between the groups are displayed. Each dot represents a sample color coded by both gender and level of arsenic exposure level. Pearson correlations were calculated between each sample of total population, and correlation coefficient values were shown by heat map of Data1 (c) and Data2 (d). The color-coding bar proves the value of correlation-coefficient. The dendrogram represents the relation between the samples created by using hierarchical clustering approach.

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