Association between Arsenic Level, Gene Expression in Asian Population, and In Vitro Carcinogenic Bladder Tumor

Figure 5

Identification of previously known arsenic exposed gene association with cancer progression. (a–d) The common arsenic exposed gene-set from Data1 and Data2 compared with differentially expressed genes within four arsenic trioxide (ATO) cell lines. Venn diagram, showing total number of common genes, (a) U266, (b) MM1S, (c) KMS11, and (d) 8226S. Interaction network functional enrichment analysis plots using STRING were demonstrated (underneath). The plots were generated with common genes identified between each cell-line and arsenic exposed gene list; the connected lines represent the degree of interconnectivity and enrichment in characteristic molecular functions.

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