Myostatin Deficiency Enhances Antioxidant Capacity of Bovine Muscle via the SMAD-AMPK-G6PD Pathway

<div>MSTN promotes muscle antioxidant capacity through G6PD in the pentose phosphate pathway. (a) The concentration of oxygen free radical in the muscles. (b) The concentration of H<sub>2</sub>O<sub>2</sub> in the muscles. (c) The concentration of malondialdehyde in the muscles. (d) The activity of mitochondrial respiratory complex I in the muscles. (e) Activity of mitochondrial respiratory complex III in the muscles. (f) The activity of GSH-Px in the muscles. (g) Activity of GR in the muscles. (h) The concentration of GSH in the muscles. (i) The concentration of GSSG in the muscles. MT: MSTN knockout cattle group; WT: wild-type cattle group. 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Oxidative Medicine and Cellular Longevity

fig3

Figure 3

Figure 3: Myostatin Deficiency Enhances Antioxidant Capacity of Bovine Muscle via the SMAD-AMPK-G6PD Pathway 